باروری و ناباروری ایران

BACKGROUND: IUI with or without ovarian stimulation (OS) has become a first-line treatment option for many infertile couples, worldwide.

The appropriate treatment modality for couples and their clinical management through IUI or IUI/OS cycles must consider maternal

and perinatal outcomes, most notably the clinical complication of higher-order multiple pregnancies associated with IUI–OS. With a current

global emphasis to continue to decrease maternal and perinatal mortality and morbidity, the World Health Organization (WHO) had

established a multi-year project to review the evidence for the establishment of normative guidance for the implementation of IUI as a

treatment to address fertility problems, and to consider its cost-effectiveness for lower resource settings.